Chien-Yen Chen’s research works focus on the bio-geo-chemical-microbiology which contained elemental biogeochemistry of environment. His research of nanotechnology is also inspired by natural architectures particularly by microorganisms and this green technology also contributes to the pollution control of waste material. The biosurfactant and foam were used for application the synthesis of materials. The bio-templated (biomimic) synthesis of nanoparticles has been applied in environmental cleanup. Environment DNA sparkles in his group when the invasive and conservational issues come to critical points now.

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