Biomaterials play a pivotal role in advancing medical applications, ranging from medical devices and cell cultivation to drug delivery and regeneration/precision medicine. The functional impact of biomaterials is heavily influenced by how they are engineered into various architectures or scaled to micro-/nano-structures, dramatically altering their interaction with biological systems. In this project, biological polymers such as gelatin, chitosan, and hyaluronic acid are utilized as drug carriers, cell scaffolds, and more, tailored for diverse disease treatments. These biomaterials find application in critical fields such as ocular health, bone/cartilage repair, skin regeneration, and cardiovascular treatments. Specifically, we aim to harness their properties for:
1. Non-invasive Drug Delivery Systems: Developing novel formulations that enhance patient compliance and targeting efficiency. This includes creating nanoformulations to address ophthalmological disorders such as retinal diseases and delivering inhalable nanomedicine for pulmonary conditions like lung fibrosis. The inhalation approach ensures high local drug concentration with targeted accumulation, improving therapeutic outcomes.
2. Ophthalmic Bioengineering: Designing biomaterials that act as scaffolds for cell regeneration and carriers for localized drug delivery in the treatment of ocular diseases. These approaches aim to advance solutions for conditions that threaten vision and overall eye health.
3. Precision Medicine: Exploring how the fabrication of biomaterials into specific micro-/nano-architectures can influence cell behavior and therapeutic outcomes. This includes using these engineered materials to improve treatment efficiency in tissue regeneration and targeted therapies.

Current research efforts include testing the therapeutic efficacy of nanoformulations for retinal diseases and optimizing lung-targeted nanomedicine delivery systems. These innovations highlight the transformative potential of biomaterials in addressing complex medical challenges.