The International Center for the Scientific Development of Shrimp Aquaculture (ICSDSA), NCKU is one of scientific evidence-based breeding center for Penaeus monodon and aims to revive and advance shrimp aquaculture in Taiwan. ICSDSA houses two World Organisation for Animal Health (WOAH, formerly known as OIE) reference laboratories for shrimp diseases (WSD and AHPND). Our team is a perfect blend of state-of-the art research laboratory, breeding center and WOAH reference laboratories and an excellent international research team. The TEEP internship program would be a great opportunity for students to have hands-on training on various experiments designed to understand the pathogenic mechanisms and host-pathogen interactions. This TEEP program will strengthen our collaboration and encourage young researchers to involve in Fishery and Aquaculture research for a better future. We aim to recruit students (Master and PhD) interested in working with shrimp diseases, shrimp feed additives and whole genome sequence comparisons of pathogenic bacterial strains. For this TEEP program we propose the following 2 topics and interested students can apply within the application deadline to participate in this project. Shrimp aquaculture is a global industry and potentially accounts for more than 70% of total production in Asian countries. However, this industry is threatened by several serious shrimp diseases, especially in developing countries in Asia. The white spot disease (WSD), caused by white spot syndrome virus (WSSV), and acute hepatopancreatic necrosis disease (AHPND), and translucent post-larvae disease (TPD) caused by a virulent strain of the Vibrio parahaemolyticus bacterium are some the harmful diseases prevalent in shrimp industry. These diseases have incurred huge economic losses globally. There is an immense need to develop effective strategies to combat these diseases. Topic 1: Genome-wide comparison of Translucent Post-larvae Disease (TPD) bacterial strains isolated from different regions. Objectives: 1. Identify the similarities and differences between TPD strains 2. Compare key pathways involved in virulence and pathogenic mechanisms 3. Investigate the prevalence of antimicrobial resistance genes 4. Identify candidate strains for the vaccine production Topic 2: Effect of insect meal supplemented feed on resistance to WSSV or V. parahaemolyticus in shrimp Objectives: 1. Investigate the disease resistance of insect meal supplemented feed 2. Determine the effect of insect meal-supplemented feed on immune status of shrimp 3. Examine the reduced dysbiosis in the shrimp stomach 4. Establish a bacterial-interaction network between pathogenic and commensal bacteria in AHPND-infected shrimp stomach